SNX8

Across TCGA patient cohorts, SNX8 mutation is significantly associated with the RNA expression of many other genes, with 1,373 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX8-associated genes across cancer lineages are MIR4665, STAU2P1, and RNU6-163P. Each is linked with SNX8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX8-to-partner and partner-to-SNX8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4665 grouped by SNX8-low versus SNX8-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX8→partner) and Y-score (partner→SNX8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MIR4665 →	+0.573	+5.289	<.001	.001	3	2
UCEC	STAU2P1 →	+0.131	+2.033	.003	.001	3	2
LIHC	RNU6-163P →	+0.317	+4.878	<.001	.005	3	2
COAD	NANOGP10 →	+0.088	+4.251	.002	.008	3	2
BLCA	RPL23AP24 →	+0.240	+7.040	<.001	<.001	3	2
SKCM	CTBP2P9 →	+0.100	+5.080	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,373 associations by consensus.

MIR4665 by SNX8 expression — LIHC

Explore this box plot interactively →