SNX4

Across TCGA cell cohorts, SNX4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,284 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SNX4-associated GO terms across cancer lineages are DNA-templated DNA replication maintenance of fidelity, Double-strand break repair, and Double-strand break repair via nonhomologous end joining. Each is linked with SNX4 in more than 15 cancer types. Because this analysis shows association rather than direction, both SNX4-to-partner and partner-to-SNX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication maintenance of fidelity grouped by SNX4-low versus SNX4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX4→partner) and Y-score (partner→SNX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication maintenance of fidelity →	+0.094	+0.899	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.074	+0.764	<.001	.002	3	15
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via nonhomologous end joining →	+0.060	+0.745	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of double-strand break repair via homologous recombination →	+0.076	+0.891	<.001	<.001	3	14
BREAST	Mitotic cytokinesis →	+0.075	+0.925	.007	<.001	3	12
BLOOD_Lymphoma	Transcription preinitiation complex assembly →	+0.066	+1.266	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,284 associations by consensus.

DNA-templated DNA replication maintenance of fidelity by SNX4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →