SNX29

Across TCGA patient cohorts, SNX29 mutation is significantly associated with the RNA expression of many other genes, with 3,355 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX29-associated genes across cancer lineages are NDUFC1, RWDD1, and GMNN. Each is linked with SNX29 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNX29-to-partner and partner-to-SNX29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDUFC1 grouped by SNX29-low versus SNX29-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX29→partner) and Y-score (partner→SNX29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NDUFC1 →	+0.422	+2.328	<.001	.003	3	3
UCEC	RWDD1 →	+0.374	+2.971	<.001	<.001	3	3
UCEC	GMNN →	+0.506	+2.593	.003	<.001	3	3
UCEC	MARK1 →	-0.756	-1.893	<.001	<.001	3	3
UCEC	MND1 →	+0.516	+1.643	.007	.003	3	3
UCEC	TNFRSF19 →	-1.017	-1.882	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,355 associations by consensus.

NDUFC1 by SNX29 expression — SKCM

Explore this box plot interactively →