SNX29

Across TCGA patient cohorts, SNX29 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX29-associated genes across cancer lineages are ATM, Caspase-7-cleavedD198, and GAPDH. Each is linked with SNX29 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNX29-to-partner and partner-to-SNX29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by SNX29-low versus SNX29-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX29→partner) and Y-score (partner→SNX29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ATM →	-0.838	-3.169	<.001	.018	3	3
UCEC	Caspase-7-cleavedD198 →	+0.627	+1.807	.001	.024	3	3
STAD	GAPDH →	+0.616	+3.000	<.001	.033	3	2
STAD	beta-Catenin →	+0.799	+3.000	.033	.036	3	2
COAD	Gab2 →	-0.542	-3.144	<.001	.019	3	2
COAD	14-3-3_epsilon →	+0.199	+3.212	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

ATM by SNX29 expression — COAD

Explore this box plot interactively →