SNX27

Across TCGA patient cohorts, SNX27 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,994 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SNX27-associated proteins across cancer lineages are RPRD2, GATAD2B, and POGZ. Each is linked with SNX27 in more than 7 cancer types. Because this analysis shows association rather than direction, both SNX27-to-partner and partner-to-SNX27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNX27 versus RPRD2 in LSCC, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX27→partner) and Y-score (partner→SNX27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RPRD2 →	+0.293	+0.547	<.001	<.001	3	8
HNSC	GATAD2B →	+0.303	+0.536	<.001	<.001	3	8
UCEC	POGZ →	+0.350	+0.665	<.001	<.001	3	6
LUAD	UBE2Q1 →	+0.272	+0.476	<.001	<.001	3	6
UCEC	BROX →	+0.451	+0.404	<.001	.005	3	6
UCEC	C1orf35 →	+0.480	+0.516	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,994 associations by consensus.

SNX27 vs RPRD2 — LSCC

Explore this scatter interactively →