SNX27

Across TCGA patient cohorts, SNX27 protein abundance is significantly associated with the RNA expression of many other genes, with 9,360 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SNX27-associated genes across cancer lineages are PEX11B, ADAR, and TARS2. Each is linked with SNX27 in more than 7 cancer types. Because this analysis shows association rather than direction, both SNX27-to-partner and partner-to-SNX27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNX27 versus PEX11B in HNSC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX27→partner) and Y-score (partner→SNX27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PEX11B →	+0.446	+0.113	.001	<.001	3	8
UCEC	ADAR →	+0.625	+0.305	<.001	<.001	3	7
BRCA	TARS2 →	+0.647	+0.278	<.001	<.001	3	6
HNSC	ENSA →	+0.540	+0.164	.006	<.001	3	6
BRCA	C1orf56 →	+0.601	+0.157	<.001	<.001	3	6
BRCA	TADA1 →	+0.582	+0.271	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,360 associations by consensus.

SNX27 vs PEX11B — HNSC

Explore this scatter interactively →