SNX27

Across TCGA patient cohorts, SNX27 mutation is significantly associated with the RNA expression of many other genes, with 5,147 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX27-associated genes across cancer lineages are RNA5SP460, RNA5SP413, and RNA5SP145. Each is linked with SNX27 in more than 2 cancer types. Because this analysis shows association rather than direction, both SNX27-to-partner and partner-to-SNX27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP460 grouped by SNX27-low versus SNX27-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX27→partner) and Y-score (partner→SNX27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5SP460 →	+0.300	+4.743	<.001	.005	3	3
UCEC	RNA5SP413 →	+1.140	+2.096	<.001	<.001	3	3
SKCM	RNA5SP145 →	+0.312	+4.402	<.001	.002	3	3
SKCM	HNRNPA1P29 →	+0.054	+3.913	<.001	.006	3	2
CESC	LINC01072 →	+0.173	+3.345	<.001	.008	3	2
CESC	LINC02559 →	+1.135	+4.927	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,147 associations by consensus.

RNA5SP460 by SNX27 expression — SKCM

Explore this box plot interactively →