SNX27

Across TCGA cell cohorts, SNX27 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,403 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNX27-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Positive regulation of organelle assembly, and Negative regulation of chromosome condensation. Each is linked with SNX27 in more than 15 cancer types. Because this analysis shows association rather than direction, both SNX27-to-partner and partner-to-SNX27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by SNX27-low versus SNX27-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX27→partner) and Y-score (partner→SNX27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Epigenetic regulation of gene expression →	+0.068	+0.719	<.001	.001	3	16
STOMACH	Positive regulation of organelle assembly →	+0.088	+1.040	<.001	<.001	3	14
OVARY	Negative regulation of chromosome condensation →	+0.156	+0.701	<.001	<.001	3	14
STOMACH	Regulation of protein sumoylation →	+0.123	+0.792	.001	.009	3	14
STOMACH	Regulation of DNA repair →	+0.064	+0.793	.001	.003	3	14
KIDNEY	Positive regulation of TORC2 signaling →	+0.095	+0.682	.002	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,403 associations by consensus.

Epigenetic regulation of gene expression by SNX27 expression — OVARY

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