SNX22

Across TCGA patient cohorts, SNX22 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,988 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNX22-associated proteins across cancer lineages are JUP, RASAL3_S831, and PECAM1. Each is linked with SNX22 in more than 5 cancer types. Because this analysis shows association rather than direction, both SNX22-to-partner and partner-to-SNX22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNX22 versus JUP in LSCC, with a Pearson correlation of -0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX22→partner) and Y-score (partner→SNX22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	JUP →	-0.615	-0.512	<.001	<.001	3	5
LSCC	RASAL3_S831 →	+0.531	+0.565	<.001	<.001	3	5
LSCC	PECAM1 →	+0.397	+0.715	<.001	<.001	3	4
COAD	IKZF1_S63 →	+0.505	+0.242	.003	.004	3	4
HNSC	LCK →	+0.455	+0.549	<.001	.001	3	4
COAD	LIMD2 →	+0.528	+0.305	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,988 associations by consensus.

SNX22 vs JUP — LSCC

Explore this scatter interactively →