SNX22

Across TCGA patient cohorts, SNX22 protein abundance is significantly associated with the RNA expression of many other genes, with 2,136 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SNX22-associated genes across cancer lineages are YPEL1, ART4, and PLCL1. Each is linked with SNX22 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX22-to-partner and partner-to-SNX22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNX22 versus YPEL1 in LSCC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX22→partner) and Y-score (partner→SNX22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	YPEL1 →	+0.554	+0.545	.007	<.001	3	2
LUAD	ART4 →	+0.834	+0.677	<.001	<.001	3	2
LSCC	PLCL1 →	+0.673	+0.442	<.001	.004	3	2
LUAD	HEMGN →	+0.338	+0.641	<.001	.001	3	2
LUAD	NTRK3 →	+0.335	+0.492	.006	<.001	3	2
LSCC	ENPP6 →	+0.498	+0.374	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,136 associations by consensus.

SNX22 vs YPEL1 — LSCC

Explore this scatter interactively →