SNX22

Across TCGA cell cohorts, SNX22 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,192 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SNX22-associated GO terms across cancer lineages are Base-excision repair, gap-filling, Positive regulation of intracellular estrogen receptor signaling pathway, and Negative regulation of myoblast fusion. Each is linked with SNX22 in more than 11 cancer types. Because this analysis shows association rather than direction, both SNX22-to-partner and partner-to-SNX22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Base-excision repair, gap-filling grouped by SNX22-low versus SNX22-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX22→partner) and Y-score (partner→SNX22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Base-excision repair, gap-filling →	+0.106	+0.512	.001	.007	3	11
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.170	+0.741	.001	.001	2	12
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.162	+0.572	.003	.004	3	10
BONE	Negative regulation of calcium ion export across plasma membrane →	+0.078	+1.117	.001	<.001	3	10
BONE	Establishment of RNA localization →	+0.110	+0.909	<.001	<.001	3	10
PANCREAS	RNA catabolic process →	+0.055	+0.726	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,192 associations by consensus.

Base-excision repair, gap-filling by SNX22 expression — PANCREAS

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