SNX21

Across TCGA patient cohorts, SNX21 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,623 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SNX21-associated proteins across cancer lineages are DNM1, DNAJC1, and FOXK1. Each is linked with SNX21 in more than 4 cancer types. Because this analysis shows association rather than direction, both SNX21-to-partner and partner-to-SNX21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNX21 versus DNM1 in BRCA, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX21→partner) and Y-score (partner→SNX21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DNM1 →	+0.423	+0.492	.001	.002	3	5
LSCC	DNAJC1 →	-0.498	-0.638	<.001	<.001	3	4
LSCC	FOXK1 →	+0.322	+0.447	<.001	.002	3	4
COAD	HID1 →	-0.506	-0.661	<.001	<.001	3	4
LUAD	SPCS2 →	-0.390	-0.603	.002	.006	3	4
LSCC	FNDC3A_S203 →	-0.397	-0.449	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,623 associations by consensus.

SNX21 vs DNM1 — BRCA

Explore this scatter interactively →