SNX21

Across TCGA patient cohorts, SNX21 protein abundance is significantly associated with the RNA expression of many other genes, with 10,973 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SNX21-associated genes across cancer lineages are RHOJ, COLEC12, and MAGI2-AS3. Each is linked with SNX21 in more than 5 cancer types. Because this analysis shows association rather than direction, both SNX21-to-partner and partner-to-SNX21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNX21 versus RHOJ in UCEC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX21→partner) and Y-score (partner→SNX21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RHOJ →	+0.938	+0.398	<.001	.001	3	6
LSCC	COLEC12 →	+0.946	+0.303	<.001	<.001	3	6
UCEC	MAGI2-AS3 →	+0.936	+0.385	.001	.002	3	6
UCEC	ADAMTS9-AS2 →	+1.056	+0.470	.001	<.001	3	6
GBM	SRPX →	+1.883	+0.369	<.001	<.001	3	5
BRCA	RECK →	+0.620	+0.260	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,973 associations by consensus.

SNX21 vs RHOJ — UCEC

Explore this scatter interactively →