SNX21

Across TCGA patient cohorts, SNX21 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX21-associated genes across cancer lineages are 4E-BP1. Each is linked with SNX21 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX21-to-partner and partner-to-SNX21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 4E-BP1 grouped by SNX21-low versus SNX21-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX21→partner) and Y-score (partner→SNX21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.481	+3.169	.001	.020	1	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

4E-BP1 by SNX21 expression — UCEC

Explore this box plot interactively →