SNX21

Across TCGA cell cohorts, SNX21 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,776 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SNX21-associated GO terms across cancer lineages are Golgi to plasma membrane protein transport, Actin filament depolymerization, and Endosomal transport. Each is linked with SNX21 in more than 15 cancer types. Because this analysis shows association rather than direction, both SNX21-to-partner and partner-to-SNX21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi to plasma membrane protein transport grouped by SNX21-low versus SNX21-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX21→partner) and Y-score (partner→SNX21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Golgi to plasma membrane protein transport →	+0.117	+1.482	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.251	+1.840	.001	.001	3	15
STOMACH	Endosomal transport →	+0.051	+1.552	.004	.007	3	14
STOMACH	Cell division →	+0.077	+2.007	<.001	<.001	3	14
BONE	Positive regulation of focal adhesion assembly →	+0.193	+1.269	<.001	<.001	3	14
BLOOD_Lymphoma	Establishment of protein localization to plasma membrane →	+0.097	+0.574	<.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,776 associations by consensus.

Golgi to plasma membrane protein transport by SNX21 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →