SNX20

Across TCGA patient cohorts, SNX20 mutation is significantly associated with the RNA expression of many other genes, with 2,648 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX20-associated genes across cancer lineages are CAD, BOLA2-SMG1P6, and MIR1203. Each is linked with SNX20 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX20-to-partner and partner-to-SNX20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAD grouped by SNX20-low versus SNX20-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX20→partner) and Y-score (partner→SNX20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CAD →	+0.665	+3.328	.003	.005	3	2
SKCM	BOLA2-SMG1P6 →	+0.587	+3.328	.003	.005	3	2
LUSC	MIR1203 →	+0.454	+3.142	<.001	.006	3	2
CESC	CUL1P1 →	+0.020	+4.320	.001	.007	3	2
BLCA	RNA5SP251 →	+0.416	+6.814	<.001	<.001	3	2
UCEC	RN7SL248P →	+0.062	+3.219	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,648 associations by consensus.

CAD by SNX20 expression — SKCM

Explore this box plot interactively →