SNX20

Across TCGA cell cohorts, SNX20 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNX20-associated genes across cancer lineages are FOXF2, TMEFF2, and JAKMIP1. Each is linked with SNX20 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX20-to-partner and partner-to-SNX20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXF2 grouped by SNX20-low versus SNX20-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX20→partner) and Y-score (partner→SNX20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FOXF2 →	+1.178	+3.491	<.001	.004	3	1
LARGE_INTESTINE	TMEFF2 →	+0.152	+3.013	.005	.005	3	1
LARGE_INTESTINE	JAKMIP1 →	+0.253	+3.506	<.001	.001	3	1
LARGE_INTESTINE	CLGN →	+1.041	+3.215	.008	.009	3	1
LARGE_INTESTINE	DRAXIN →	+0.356	+3.415	.001	.004	3	1
LARGE_INTESTINE	OR2C1 →	+0.105	+3.047	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

FOXF2 by SNX20 expression — LARGE_INTESTINE

Explore this box plot interactively →