Across TCGA patient cohorts, SNX2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,401 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SNX2-associated genes across cancer lineages are BTK, ATP8B4, and CPVL. Each is linked with SNX2 in more than 8 cancer types. Because this analysis shows association rather than direction, both SNX2-to-partner and partner-to-SNX2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX2→partner) and Y-score (partner→SNX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BTK →	+0.847	+0.226	<.001	<.001	3	9
HNSC	ATP8B4 →	+0.751	+0.266	<.001	<.001	3	8
HNSC	CPVL →	+1.234	+0.308	<.001	<.001	3	8
GBM	MS4A6A →	+1.177	+0.234	<.001	<.001	3	8
GBM	VENTX →	+1.004	+0.186	<.001	<.001	3	8
LSCC	SCIMP →	+0.690	+0.235	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,401 associations by consensus.

Exploration

SNX2 survival (RNA) · tumor vs normal (RNA) · all SNX2 data types