Across TCGA patient cohorts, SNX2 mutation is significantly associated with the RNA expression of many other genes, with 4,689 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX2-associated genes across cancer lineages are HSPA8P17, UBE2V1P12, and OR6K3. Each is linked with SNX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX2-to-partner and partner-to-SNX2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX2→partner) and Y-score (partner→SNX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	HSPA8P17 →	+0.092	+4.927	<.001	.002	3	2
COAD	UBE2V1P12 →	+0.075	+4.602	<.001	.003	3	2
BLCA	OR6K3 →	+0.069	+5.106	.007	.008	3	2
UCEC	TADA2A →	+0.331	+2.727	.001	<.001	3	2
BRCA	RNU6-928P →	+0.648	+5.841	<.001	.003	3	2
LUSC	MIR3713 →	+0.529	+5.081	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,689 associations by consensus.

Exploration

SNX2 survival (RNA) · tumor vs normal (RNA) · all SNX2 data types