Across TCGA cell cohorts, SNX2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SNX2-associated genes across cancer lineages are OR2V1, CD300H, and APCS. Each is linked with SNX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX2-to-partner and partner-to-SNX2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX2→partner) and Y-score (partner→SNX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR2V1 →	+0.042	+4.095	.004	.009	3	1
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1
BLOOD_Leukemia	APCS →	+0.128	+5.201	<.001	.006	3	1
BLOOD_Leukemia	LCE1C →	+0.432	+4.922	.002	.009	3	1
BLOOD_Leukemia	SLC5A8 →	+0.182	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR10A6 →	+0.044	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

SNX2 survival (RNA) · tumor vs normal (RNA) · all SNX2 data types