SNX16

Across TCGA cell cohorts, SNX16 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SNX16-associated genes across cancer lineages are EPPIN, ADAM30, and C1orf87. Each is linked with SNX16 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX16-to-partner and partner-to-SNX16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EPPIN grouped by SNX16-low versus SNX16-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX16→partner) and Y-score (partner→SNX16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	EPPIN →	+0.006	+4.922	.005	.009	3	1
BLOOD_Leukemia	ADAM30 →	+0.023	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	C1orf87 →	+0.015	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OR9K2 →	+0.022	+5.539	<.001	.003	3	1
BLOOD_Leukemia	OR1A1 →	+0.012	+4.922	<.001	.009	3	1
BLOOD_Leukemia	MRGPRX4 →	+0.022	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

EPPIN by SNX16 expression — BLOOD_Leukemia

Explore this box plot interactively →