SNX14

Across TCGA patient cohorts, SNX14 mutation is significantly associated with the RNA expression of many other genes, with 5,338 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX14-associated genes across cancer lineages are LINC02559, RN7SL248P, and CICP12. Each is linked with SNX14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX14-to-partner and partner-to-SNX14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02559 grouped by SNX14-low versus SNX14-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX14→partner) and Y-score (partner→SNX14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC02559 →	+1.329	+5.342	<.001	.002	3	2
CESC	RN7SL248P →	+0.121	+6.584	<.001	<.001	3	2
SKCM	CICP12 →	+0.167	+3.685	<.001	.004	3	2
UCEC	DDX19B →	+0.346	+2.085	<.001	<.001	3	2
UCEC	CDC25C →	+0.502	+2.939	.003	<.001	3	2
UCEC	PKN3 →	+1.038	+4.868	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,338 associations by consensus.

LINC02559 by SNX14 expression — CESC

Explore this box plot interactively →