SNX12

Across TCGA patient cohorts, SNX12 mutation is significantly associated with the RNA expression of many other genes, with 272 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNX12-associated genes across cancer lineages are SEPTIN14P19, MIR6786, and RNU6-380P. Each is linked with SNX12 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNX12-to-partner and partner-to-SNX12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEPTIN14P19 grouped by SNX12-low versus SNX12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNX12→partner) and Y-score (partner→SNX12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SEPTIN14P19 →	+0.027	+3.923	<.001	.009	3	2
HNSC	MIR6786 →	+0.323	+7.954	<.001	.008	3	2
UCEC	RNU6-380P →	+0.170	+4.148	<.001	.006	3	2
BLCA	FTLP18 →	+0.089	+7.640	<.001	.009	3	2
HNSC	MBD3L4 →	+0.059	+7.954	<.001	.008	3	1
UCEC	IGHV1OR15-6 →	+0.325	+2.833	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 272 associations by consensus.

SEPTIN14P19 by SNX12 expression — UCEC

Explore this box plot interactively →