SNRPN

Across TCGA patient cohorts, SNRPN protein abundance is significantly associated with the RNA expression of many other genes, with 236 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNRPN-associated genes across cancer lineages are MFNG, STAG3L4, and MS4A6A. Each is linked with SNRPN in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRPN-to-partner and partner-to-SNRPN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNRPN versus MFNG in BRCA, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPN→partner) and Y-score (partner→SNRPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MFNG →	+0.961	+1.929	<.001	.002	3	1
BRCA	STAG3L4 →	-0.976	-2.239	.001	.002	3	1
BRCA	MS4A6A →	+0.879	+1.485	.001	.007	3	1
BRCA	UTP18 →	-0.725	-1.447	.006	.006	3	1
BRCA	GZMK →	+1.481	+1.614	.008	.001	3	1
BRCA	IRAG2 →	+0.662	+1.423	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 236 associations by consensus.

SNRPN vs MFNG — BRCA

Explore this scatter interactively →