Across TCGA pan-cancer cohorts, SNRPGP17 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SNRPGP17’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where SNRPGP17 RNA is repressed in tumor relative to normal tissue. In most cancer types SNRPGP17 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA and PRAD are the cancer types where SNRPGP17 tumor–normal differential expression is most reproducible.