SNRPEP11

Across TCGA pan-cancer cohorts, SNRPEP11 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated SNRPEP11 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SNRPEP11 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNRPEP11 expression acts as an unfavorable survival marker, although some lineages such as KIRC and DLBC show a favorable association.

ACC, KIRP, and KIRC are the cancer types where SNRPEP11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.455	0.791	<.001	127	view →
KIRP	DFS	Median	III,IV	0.137	0.622	<.001	62	view →
KIRC	DFS	Tertile	III,IV	0.779	0.415	.001	54	view →
UCEC	DFS	Median	All	0.563	0.718	<.001	54	view →
BRCA	OS	Quartile	All	0.489	0.595	<.001	28	view →
PAAD	OS	Median	All	0.417	0.568	.006	26	view →
STAD	OS	Quartile	II,III,IV	0.498	0.800	.006	20	view →
HNSC	DFS	Median	II,III,IV	0.634	0.751	.004	18	view →
PRAD	DFS	Quartile	All	0.693	0.918	.002	18	view →
DLBC	DFS	Median	III,IV	1.000	0.457	.003	17	view →
LUAD	OS	Tertile	All	0.774	0.888	.005	16	view →
LUSC	OS	Tertile	All	0.728	0.583	.003	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

SNRPEP11–ACC (OS)

Open the ACC breakdown →