SNRPE

Across TCGA cell cohorts, SNRPE RNA expression is significantly associated with the go_rna of many other GO terms, with 5,198 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SNRPE-associated GO terms across cancer lineages are DNA replication, Negative regulation of DNA-templated DNA replication, and DNA-templated DNA replication. Each is linked with SNRPE in more than 16 cancer types. Because this analysis shows association rather than direction, both SNRPE-to-partner and partner-to-SNRPE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication grouped by SNRPE-low versus SNRPE-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPE→partner) and Y-score (partner→SNRPE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	DNA replication →	+0.088	+0.850	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Negative regulation of DNA-templated DNA replication →	+0.146	+0.744	<.001	.006	3	16
OVARY	DNA-templated DNA replication →	+0.099	+0.820	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	DNA replication checkpoint signaling →	+0.183	+0.922	<.001	.001	3	16
OESOPHAGUS	U1 snRNA 3'-end processing →	+0.144	+0.808	<.001	<.001	3	16
OESOPHAGUS	U5 snRNA 3'-end processing →	+0.144	+0.808	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,198 associations by consensus.

DNA replication by SNRPE expression — LIVER

Explore this box plot interactively →