SNRPD3

Across TCGA patient cohorts, SNRPD3 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRPD3-associated genes across cancer lineages are Annexin-1, Fibronectin, and Notch1. Each is linked with SNRPD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRPD3-to-partner and partner-to-SNRPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by SNRPD3-low versus SNRPD3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPD3→partner) and Y-score (partner→SNRPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.853	+3.019	.001	.019	3	2
UCEC	Fibronectin →	-0.380	-3.160	.021	.019	3	1
UCEC	Notch1 →	+0.183	+2.820	.009	.035	3	1
UCEC	p62 Lck ligand →	+0.466	+3.009	.004	.019	3	1
UCEC	XBP1 →	-0.240	-2.986	<.001	.035	3	1
UCEC	Caspase-8 →	-0.310	-3.143	.014	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Annexin-1 by SNRPD3 expression — UCEC

Explore this box plot interactively →