SNRPC

Across TCGA pan-cancer cohorts, SNRPC mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated SNRPC data layer compared with 27 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SNRPC mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SNRPC expression acts as an unfavorable survival marker, although some lineages such as LUAD and COAD show a favorable association.

LUAD, COAD, and GBM are the cancer types where SNRPC mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.981	0.812	<.001	70	view →
COAD	DFS	Median	All	1.000	0.889	.024	24	view →
GBM	OS	Median	All	0.490	0.280	.005	16	view →
PDAC	OS	Quartile	III,IV	0.110	0.607	.006	12	view →
HNSC	DFS	Median	III,IV	0.687	0.890	.006	11	view →
LSCC	OS	Tertile	All	1.000	0.940	.033	5	view →
CCRCC	DFS	Quartile	III,IV	0.734	1.000	.024	4	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SNRPC–LUAD (DFS)

Open the LUAD breakdown →