SNRPB2

Across TCGA pan-cancer cohorts, SNRPB2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SNRPB2 data layer compared with 26 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SNRPB2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SNRPB2 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, HNSC, and LSCC are the cancer types where SNRPB2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.887	.022	12	view →
HNSC	OS	Median	All	0.800	0.894	.010	12	view →
LSCC	DFS	Tertile	II,III,IV	0.860	0.543	.015	12	view →
LUAD	OS	Quartile	All	0.987	0.563	.011	7	view →
GBM	OS	Quartile	All	0.548	0.269	.016	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SNRPB2–COAD (DFS)

Open the COAD breakdown →