SNRPB2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNRPB2 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRPB2-associated genes across cancer lineages are Osteoblast, Smooth muscle, and MSC. Each is linked with SNRPB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRPB2-to-partner and partner-to-SNRPB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Osteoblast grouped by SNRPB2-low versus SNRPB2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPB2→partner) and Y-score (partner→SNRPB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECOsteoblast →-0.052-2.978.048.03731
UCECSmooth muscle →-0.143-2.989.049.03731
UCECMSC →+0.301+3.000.012.03721
UCECBasophils →+0.259+3.000.008.03711
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Osteoblast by SNRPB2 expression — UCEC

Box plot of Osteoblast in SNRPB2-low vs SNRPB2-high samples in UCEC.

Explore this box plot interactively →

Exploration