SNRPA1

Across TCGA patient cohorts, SNRPA1 mutation is significantly associated with the RNA expression of many other genes, with 66 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRPA1-associated genes across cancer lineages are LINC00709, IQCF6, and E2F6P1. Each is linked with SNRPA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRPA1-to-partner and partner-to-SNRPA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00709 grouped by SNRPA1-low versus SNRPA1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPA1→partner) and Y-score (partner→SNRPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC00709 →	+0.079	+7.930	<.001	.008	3	2
UCEC	IQCF6 →	+0.478	+3.450	<.001	.006	3	2
UCEC	E2F6P1 →	+0.052	+4.660	<.001	.003	3	2
UCEC	RNA5SP418 →	+0.985	+2.863	<.001	.009	3	2
UCEC	RNU6ATAC9P →	+0.439	+3.134	.003	.005	3	2
HNSC	RNU6-1227P →	+0.493	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

LINC00709 by SNRPA1 expression — LUAD

Explore this box plot interactively →