SNRPA

Across TCGA pan-cancer cohorts, SNRPA Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated SNRPA data layer compared with 25 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher SNRPA Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SNRPA expression acts as an unfavorable survival marker.

BRCA, PAAD, and HNSC are the cancer types where SNRPA Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.211	0.924	<.001	36	view →
PAAD	DFS	Median	All	0.068	0.484	<.001	24	view →
HNSC	OS	Median	All	0.069	0.768	<.001	24	view →
LUSC	OS	Median	II,III,IV	0.248	0.745	.002	24	view →
COAD	OS	Median	III,IV	0.140	0.783	.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LGG	OS	Median	All	0.306	0.799	.009	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SNRPA–BRCA (OS)

Open the BRCA breakdown →