SNRPA

Across TCGA pan-cancer cohorts, SNRPA RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of SNRPA’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SNRPA RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNRPA is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, COAD, and KIRP are the cancer types where SNRPA tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNRPA RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.783	<.001	12	view →
COAD	Female	II,III,IV	+0.964	<.001	11	view →
KIRP	Male	II,III,IV	+0.865	<.001	11	view →
LIHC	Female	II,III,IV	+1.496	<.001	9	view →
LUSC	Female	II,III,IV	+1.271	<.001	9	view →
STAD	Male	II,III,IV	+1.027	<.001	9	view →
BLCA	All	All	+0.850	<.001	9	view →
LUAD	Male	III,IV	+0.723	<.001	9	view →
HNSC	Male	IV	+0.852	<.001	8	view →
UCEC	All	All	+0.474	<.001	6	view →
CHOL	Male	All	+2.425	<.001	5	view →
KICH	Female	All	−1.047	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

SNRPA–KIRC

Open the KIRC breakdown →