SNRPA

Across TCGA cell cohorts, SNRPA RNA expression is significantly associated with the go_rna of many other GO terms, with 5,574 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SNRPA-associated GO terms across cancer lineages are DNA replication initiation, Positive regulation of nuclear cell cycle DNA replication, and Lagging strand elongation. Each is linked with SNRPA in more than 17 cancer types. Because this analysis shows association rather than direction, both SNRPA-to-partner and partner-to-SNRPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by SNRPA-low versus SNRPA-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPA→partner) and Y-score (partner→SNRPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication initiation →	+0.195	+0.769	<.001	<.001	3	18
SOFT_TISSUE	Positive regulation of nuclear cell cycle DNA replication →	+0.123	+0.687	<.001	<.001	3	18
BLOOD_Myeloma	Lagging strand elongation →	+0.171	+0.867	<.001	<.001	3	18
BONE	DNA replication checkpoint signaling →	+0.234	+0.909	<.001	.001	3	17
OESOPHAGUS	DNA-templated DNA replication →	+0.118	+0.556	.006	.006	3	17
KIDNEY	Protein-DNA complex disassembly →	+0.182	+0.802	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,574 associations by consensus.

DNA replication initiation by SNRPA expression — BONE

Explore this box plot interactively →