SNRPA

Across TCGA cell cohorts, SNRPA mutation is significantly associated with the drug of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNRPA-associated genes across cancer lineages are AZD5153, JAK1_8709, and 50869. Each is linked with SNRPA in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRPA-to-partner and partner-to-SNRPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AZD5153 grouped by SNRPA-low versus SNRPA-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRPA→partner) and Y-score (partner→SNRPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AZD5153 →	+0.623	+2.649	.012	.046	3	1
LARGE_INTESTINE	JAK1_8709 →	+0.464	+2.649	.018	.046	3	1
LARGE_INTESTINE	50869 →	+0.445	+2.649	.035	.046	3	1
LARGE_INTESTINE	ETP-45835 →	+0.272	+2.652	.024	.045	3	1
LARGE_INTESTINE	Y-39983 →	+0.569	+2.652	.007	.045	2	1
LARGE_INTESTINE	I-BET-762 →	+0.490	+2.646	.045	.047	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

AZD5153 by SNRPA expression — LARGE_INTESTINE

Explore this box plot interactively →