Across TCGA patient cohorts, SNRNP35 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRNP35-associated genes across cancer lineages are EGFR_pY1068, INPP4B, and PCNA. Each is linked with SNRNP35 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRNP35-to-partner and partner-to-SNRNP35 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRNP35→partner) and Y-score (partner→SNRNP35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.244	-2.115	.026	.019	3	1
UCEC	INPP4B →	-0.365	-3.459	.009	.005	3	1
UCEC	PCNA →	+0.276	+2.321	.003	.034	3	1
UCEC	PDCD4 →	-0.679	-3.321	<.001	.009	3	1
UCEC	Rab25 →	-0.470	-2.321	.001	.034	3	1
UCEC	Smac →	+0.275	+2.999	.015	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

SNRNP35 survival (RNA) · tumor vs normal (RNA) · all SNRNP35 data types