SNRNP27

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNRNP27 mutation is significantly associated with the RNA expression of many other genes, with 103 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRNP27-associated genes across cancer lineages are MIR6894, RNA5SP168, and MIR6870. Each is linked with SNRNP27 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRNP27-to-partner and partner-to-SNRNP27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6894 grouped by SNRNP27-low versus SNRNP27-high in ESCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRNP27→partner) and Y-score (partner→SNRNP27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCAMIR6894 →+0.480+5.954<.001.00232
UCECRNA5SP168 →+0.437+4.206.007.00132
UCECMIR6870 →+0.588+3.344<.001.00831
UCECRNA5SP26 →+0.318+4.923<.001.00231
UCECRNU4-82P →+0.764+4.092<.001.00131
UCECRNA5SP361 →+0.269+4.555<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 103 associations by consensus.

MIR6894 by SNRNP27 expression — ESCA

Box plot of MIR6894 in SNRNP27-low vs SNRNP27-high samples in ESCA.

Explore this box plot interactively →

Exploration