SNRNP27

Across TCGA pan-cancer cohorts, SNRNP27 RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated SNRNP27 data layer compared with 6 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher SNRNP27 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNRNP27 expression acts as an unfavorable survival marker, although some lineages such as KIRC and OV show a favorable association.

KIRP, HNSC, and ACC are the cancer types where SNRNP27 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	III,IV	0.099	0.603	.001	80	view →
HNSC	OS	Quartile	All	0.572	0.764	.001	78	view →
ACC	DFS	Median	All	0.410	0.741	<.001	69	view →
LIHC	OS	Median	All	0.692	0.862	<.001	58	view →
CESC	DFS	Median	II,III,IV	0.261	0.615	.002	56	view →
ESCA	DFS	Tertile	All	0.387	0.656	<.001	44	view →
KIRC	DFS	Quartile	All	0.858	0.674	.005	31	view →
LUAD	DFS	Quartile	All	0.734	0.880	.005	29	view →
KICH	OS	Median	II,III,IV	0.643	0.958	.005	27	view →
LUSC	DFS	Tertile	III,IV	0.335	0.661	.004	27	view →
OV	OS	Tertile	IV	0.730	0.417	.011	26	view →
UCEC	DFS	Tertile	All	0.654	0.827	.001	24	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

SNRNP27–KIRP (DFS)

Open the KIRP breakdown →