SNRNP27

Across TCGA cell cohorts, SNRNP27 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,584 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SNRNP27-associated GO terms across cancer lineages are Purine deoxyribonucleoside monophosphate biosynthetic process, DAMP biosynthetic process, and Regulation of DNA damage checkpoint. Each is linked with SNRNP27 in more than 10 cancer types. Because this analysis shows association rather than direction, both SNRNP27-to-partner and partner-to-SNRNP27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine deoxyribonucleoside monophosphate biosynthetic process grouped by SNRNP27-low versus SNRNP27-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRNP27→partner) and Y-score (partner→SNRNP27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.110	+0.656	<.001	<.001	3	11
URINARY_TRACT	DAMP biosynthetic process →	+0.110	+0.656	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA damage checkpoint →	+0.093	+0.854	<.001	<.001	3	10
SOFT_TISSUE	Positive regulation of endoplasmic reticulum tubular network organization →	+0.111	+0.752	<.001	<.001	3	10
BLOOD_Myeloma	Vesicle fusion with Golgi apparatus →	+0.177	+0.977	<.001	<.001	3	10
CNS	Protein neddylation →	+0.073	+0.365	.001	.008	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,584 associations by consensus.

Purine deoxyribonucleoside monophosphate biosynthetic process by SNRNP27 expression — URINARY_TRACT

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