SNRNP200

Across TCGA pan-cancer cohorts, SNRNP200 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SNRNP200 data layer compared with 28 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SNRNP200 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SNRNP200 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

HNSC, CCRCC, and LUAD are the cancer types where SNRNP200 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.234	0.895	<.001	71	view →
CCRCC	OS	Median	All	0.885	1.000	.002	25	view →
LUAD	OS	Quartile	II,III,IV	0.899	0.372	.026	17	view →
LSCC	DFS	Median	II,III,IV	0.812	0.586	.029	2	view →
PDAC	DFS	Median	II,III,IV	0.629	0.808	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SNRNP200–HNSC (DFS)

Open the HNSC breakdown →