SNRNP200

Across TCGA pan-cancer cohorts, SNRNP200 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of SNRNP200’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SNRNP200 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SNRNP200 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

HNSC, COAD, and KIRP are the cancer types where SNRNP200 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SNRNP200 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.870	<.001	11	view →
COAD	Female	All	+0.777	<.001	10	view →
KIRP	All	IV	+1.117	.005	9	view →
LIHC	Female	II,III,IV	+1.302	<.001	8	view →
LUAD	Male	All	+0.767	<.001	8	view →
BLCA	All	All	+0.518	<.001	8	view →
LUSC	Male	II,III,IV	+1.091	<.001	7	view →
STAD	Male	II,III,IV	+1.325	<.001	6	view →
BRCA	All	II,III,IV	+0.241	.003	6	view →
CHOL	All	All	+2.025	<.001	5	view →
KICH	All	All	−0.785	<.001	5	view →
KIRC	All	All	+0.325	.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

SNRNP200–HNSC

Open the HNSC breakdown →