SNRNP200

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNRNP200 mutation is significantly associated with the RNA expression of many other genes, with 4,942 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRNP200-associated genes across cancer lineages are OIP5, EMID1, and SFXN1. Each is linked with SNRNP200 in more than 3 cancer types. Because this analysis shows association rather than direction, both SNRNP200-to-partner and partner-to-SNRNP200 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OIP5 grouped by SNRNP200-low versus SNRNP200-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRNP200→partner) and Y-score (partner→SNRNP200) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECOIP5 →+0.680+1.809<.001<.00134
UCECEMID1 →-1.012-2.311<.001<.00134
COADSFXN1 →+0.471+3.362<.001.00434
UCECZNF367 →+0.703+1.788<.001<.00134
UCECHINT1 →+0.296+1.536.005.00134
UCECTYMS →+0.679+1.963<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,942 associations by consensus.

OIP5 by SNRNP200 expression — UCEC

Box plot of OIP5 in SNRNP200-low vs SNRNP200-high samples in UCEC.

Explore this box plot interactively →

Exploration