SNRNP200

Across TCGA patient cohorts, SNRNP200 mutation is significantly associated with the total protein of many other genes, with 55 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNRNP200-associated genes across cancer lineages are IGFBP2, MEK1, and Caspase-7-cleavedD198. Each is linked with SNRNP200 in more than 3 cancer types. Because this analysis shows association rather than direction, both SNRNP200-to-partner and partner-to-SNRNP200 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGFBP2 grouped by SNRNP200-low versus SNRNP200-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRNP200→partner) and Y-score (partner→SNRNP200) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	IGFBP2 →	-0.562	-3.000	.032	.033	3	3
UCEC	MEK1 →	+0.363	+2.392	<.001	<.001	3	3
UCEC	Caspase-7-cleavedD198 →	+0.758	+1.954	<.001	<.001	3	3
STAD	eEF2 →	+0.257	+2.584	.042	.010	3	2
STAD	GSK-3_pS9 →	-0.322	-2.584	.040	.010	3	2
STAD	Lck →	+0.414	+2.828	<.001	.033	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

IGFBP2 by SNRNP200 expression — STAD

Explore this box plot interactively →