SNRNP200

Across TCGA cell cohorts, SNRNP200 mutation is significantly associated with the RNA expression of many other genes, with 542 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SNRNP200-associated genes across cancer lineages are DNASE2B, SPATA19, and SERTM2. Each is linked with SNRNP200 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNRNP200-to-partner and partner-to-SNRNP200 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNASE2B grouped by SNRNP200-low versus SNRNP200-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRNP200→partner) and Y-score (partner→SNRNP200) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	DNASE2B →	+0.227	+3.584	.002	.009	3	2
BREAST	SPATA19 →	+0.027	+4.781	<.001	.003	3	2
SKIN	SERTM2 →	+0.954	+3.906	<.001	.001	3	2
BLOOD_Leukemia	LRCOL1 →	+0.319	+3.442	<.001	.005	3	2
BLOOD_Lymphoma	HTR3D →	+0.007	+3.662	<.001	.009	3	2
LARGE_INTESTINE	ZBED3 →	+0.841	+3.169	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 542 associations by consensus.

DNASE2B by SNRNP200 expression — URINARY_TRACT

Explore this box plot interactively →