SNRK

Across TCGA patient cohorts, SNRK protein abundance is significantly associated with the RNA expression of many other genes, with 14,020 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SNRK-associated genes across cancer lineages are CLDN5, PPP1R16B, and ASPA. Each is linked with SNRK in more than 5 cancer types. Because this analysis shows association rather than direction, both SNRK-to-partner and partner-to-SNRK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNRK versus CLDN5 in CCRCC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNRK→partner) and Y-score (partner→SNRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CLDN5 →	+1.040	+0.361	<.001	<.001	3	6
GBM	PPP1R16B →	+1.290	+0.278	<.001	<.001	3	5
CCRCC	ASPA →	+1.058	+0.273	<.001	.001	3	5
CCRCC	MYCT1 →	+0.899	+0.370	<.001	<.001	3	5
UCEC	PDE1B →	+0.698	+0.341	<.001	<.001	3	5
CCRCC	RAMP2 →	+0.934	+0.388	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,020 associations by consensus.

SNRK vs CLDN5 — CCRCC

Explore this scatter interactively →