SNPH

Across TCGA patient cohorts, SNPH RNA expression is significantly associated with the protein abundance of many other proteins, with 14,288 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNPH-associated proteins across cancer lineages are SEPTIN4, SNPH_S204, and STXBP1. Each is linked with SNPH in more than 4 cancer types. Because this analysis shows association rather than direction, both SNPH-to-partner and partner-to-SNPH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNPH versus SEPTIN4 in OV, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SNPH→partner) and Y-score (partner→SNPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SEPTIN4 →	+0.551	+0.632	.002	.004	3	5
BRCA	SNPH_S204 →	+2.201	+1.630	<.001	<.001	3	4
GBM	STXBP1 →	+0.737	+0.614	<.001	<.001	3	4
BRCA	PUS7 →	-0.492	-0.923	<.001	.003	3	4
BRCA	BOP1 →	-0.433	-0.952	<.001	<.001	3	4
GBM	CAP2 →	+0.395	+0.925	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,288 associations by consensus.

SNPH vs SEPTIN4 — OV

Explore this scatter interactively →