SNPH

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNPH protein abundance is significantly associated with the protein abundance of many other proteins, with 15,217 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SNPH-associated proteins across cancer lineages are SPATS2L_T498, STARD10, and TCOF1_T249. Each is linked with SNPH in more than 2 cancer types. Because this analysis shows association rather than direction, both SNPH-to-partner and partner-to-SNPH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SNPH versus SPATS2L_T498 in GBM, with a Pearson correlation of -0.49.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SNPH→partner) and Y-score (partner→SNPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSPATS2L_T498 →-0.900-0.726.001<.00132
BRCASTARD10 →+0.762+0.812.002.00132
BRCATCOF1_T249 →-0.659-0.785<.001<.00132
GBMTRIT1_S455 →-0.759-0.475<.001<.00132
BRCAVGLL4_S58 →-0.703-0.889<.001<.00132
GBMZMYM4_S122 →-0.625-0.694<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,217 associations by consensus.

SNPH vs SPATS2L_T498 — GBM

Per-sample scatter of SNPH vs SPATS2L_T498 in GBM (Pearson r = -0.49).

Explore this scatter interactively →

Exploration