SNORD91B

Across TCGA pan-cancer cohorts, SNORD91B RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated SNORD91B data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SNORD91B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SNORD91B expression acts as an unfavorable survival marker, although some lineages such as STAD and BRCA show a favorable association.

COAD, STAD, and PCPG are the cancer types where SNORD91B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Quartile	IV	0.424	0.780	.005	39	view →
STAD	OS	Median	III,IV	0.488	0.285	.003	25	view →
PCPG	OS	Quartile	All	0.881	1.000	<.001	20	view →
UVM	OS	Tertile	III,IV	0.304	0.685	.014	17	view →
BRCA	OS	Quartile	IV	0.800	0.221	.009	16	view →
LGG	OS	Median	All	0.765	0.851	.004	16	view →
PAAD	OS	Quartile	II,III,IV	0.716	0.419	.021	13	view →
MESO	DFS	Quartile	IV	0.130	0.490	.003	12	view →
KIRC	DFS	Quartile	All	0.539	0.688	.014	12	view →
ESCA	OS	Quartile	II,III,IV	0.565	0.790	.016	7	view →
KIRP	DFS	Median	IV	0.040	0.593	.012	7	view →
LUSC	DFS	Median	IV	0.134	0.827	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

SNORD91B–COAD (OS)

Open the COAD breakdown →