SNORD64

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SNORD64 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SNORD64-associated genes across cancer lineages are MIR548H3, GLTPP1, and MIR4497. Each is linked with SNORD64 in more than 1 cancer types. Because this analysis shows association rather than direction, both SNORD64-to-partner and partner-to-SNORD64 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR548H3 grouped by SNORD64-low versus SNORD64-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SNORD64→partner) and Y-score (partner→SNORD64) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR548H3 →+0.699+5.299<.001.00631
UCECGLTPP1 →+0.187+5.081<.001.00831
UCECMIR4497 →+1.099+5.358<.001.00631
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MIR548H3 by SNORD64 expression — UCEC

Box plot of MIR548H3 in SNORD64-low vs SNORD64-high samples in UCEC.

Explore this box plot interactively →

Exploration